• Addressing whether impaired activation of D and D receptors

  2020-01-06

  

  Addressing whether impaired activation of D1 and D2 receptors regulates memory capacity is relevant for all human pathologies that lead to reduced activation of these mps1 pathways, such as ageing [39], certain genetic polymorphisms [40] and neurodegenerative disorders. In this study, we have teste

• Eggs have been recognized as

  2020-01-06

  

  Eggs have been recognized as an important contributor of functional ingredients for humans [3]. Egg yolk is composed of various biologically active proteins. The water-soluble proteins of egg yolk have been examined for their functional effects on longitudinal bone growth during the growth period in

• Bovine collagen type II a

  2020-01-06

  

  Bovine collagen type II, a fibrillar collagen mainly found in cartilage, comprises 24 potentially glycosylated lysine residues within its collagen domain. Detailed analysis revealed that 22 out of 23 of these lysine residues are hydroxylated and carry variable numbers of Gal(β1-O) and Glc(α1-2)Gal(β

• d-amphetamine receptor Gastrointestinal tone can be effectiv

  2020-01-06

  

  Gastrointestinal tone can be effectively modulated by cholinesterase inhibitors. As parasympathetic fibers release d-amphetamine receptor to contract the circular and longitudinal intestinal muscles, AChE inhibition can facilitate those actions. Postoperative ileus (delayed gastric emptying after s

• In mouse lung arsenite enhances the formation

  2020-01-06

  

  In mouse lung, arsenite enhances the formation of cigarette smoke-induced 8-oxodeoxyguanine (Hays et al., 2006) and BaP-induced DNA adducts (Evans et al., 2004). Moreover, arsenite inhibits the repair of BaP-induced DNA adducts in human lung carcinoma A549 HU 308 synthesis (Schwerdtle et al., 2003),

• Introduction Primitive neuroectodermal tumors PNETs are mali

  2020-01-06

  

  Introduction Primitive neuroectodermal tumors (PNETs) are malignant, small round cell tumors of neural crest origin which typically arises from bone or soft tissue in the trunk/axial skeleton/paraspinal regions in adolescents and young adults and comprises of 50% cases with local recurrence and met

• EphB and ephrinB mRNA levels were determined from

  2020-01-06

  

  EphB4 and ephrinB2 mRNA levels were determined from three parts taken from each tumor, and each sample was analyzed in triplicate. The differences in the histoscores and mRNA levels of EphB4 and ephrinB2 were analyzed by Student\'s t test. The correlation coefficients were evaluated both by linear r

• cAMP mediated signaling pathways are important for

  2020-01-06

  

  cAMP-mediated signaling pathways are important for maintaining metabolic homeostasis, and the effects of the glucagon/catecholamine–cAMP–PKA axis on energy balance have been well documented [20]. For example, cpi-613 of the PKA 2β regulatory subunit (RIIβ) in mice leads to increased expression of un

• br Experimental br Results and discussion

  2020-01-06

  

  Experimental Results and discussion Conclusions The fungus Mucor circinelloides MUT44, previously shown to have ene-reductase activity [11], possesses ten genes coding for putative ene-reductases belonging to the Old Yellow Enzymes family. Since the reduction of CC double bonds is one of th

• Materials and methods br Results Assay of botulinum toxin ac

  2020-01-06

  

  Materials and methods Results Assay of botulinum toxin activity is critical for the risk-assessment, diagnosis, and treatment of botulism cases. The frequently encountered active forms of the toxin are; L chain (inside intoxicated neuronal cells), BoNT (in the blood stream of a botulism patient,

• br Funding br Disclosure of interest br

  2020-01-06

  

  Funding Disclosure of interest Acknowledgments Introduction Pulmonary fibrosis (PF) is a chronic disease characterized by extensive deposits of the extracellular matrix (ECM) that can impair the architecture and function of the lungs (Cavazza et al., 2010). Imbalance between the prolifer

• The current study demonstrates a link between heme metabolis

  2020-01-06

  

  The current study demonstrates a link between heme metabolism and mitochondrial Co-I, which deficits instigate abnormalities in the metabolism of heme and its downstream targets both in-vitro in patients and healthy subjects derived LCLs and in-vivo in brains of SZ-rat model. A further study of the

• br Materials and methods br Results br Discussion Tuberculos

  2020-01-06

  

  Materials and methods Results Discussion Tuberculosis is caused by the mycobacterium M. tuberculosis, a pathogen able to survive in the hostile conditions through sophisticated defence mechanisms. In an attempt to clarify some aspects of the M. tuberculosis defence mechanisms, we have inves

• In principle in vitro techniques for assessing enzyme induct

  2020-01-03

  

  In principle, in vitro techniques for assessing enzyme induction might include the use of cultured hepatocytes, precision-cut liver slices, immortalized Fomepizole lines (such as those derived from hepatomas) and reporter gene constructs (where appropriate cells are transfected with recombinant DNA

• Mother rats acutely treated with quinpirole and mg kg decrea

  2020-01-03

  

  Mother rats acutely treated with quinpirole (0.5 and 1.0 mg/kg) decreased the pup exploration time but increased the object exploration, so they showed a significantly lower pup preference ratio. They also showed impaired maternal performance in the home cage, consistent with our previous study (Zha

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