• PJ34 hydrochloride Effect of a C C double bond The presence

  2019-08-01

  Effect of a C4-C5 double bond — The presence of a double bond at the substrate’s C4-C5 position affects the reactivity of Δ1-KSTDs to varying extent, depending on the enzyme.

• br Acknowledgements This work was

  2019-07-31

  Acknowledgements This work was supported by National Natural Science Foundation of China (No. 81400241).

• We recently described the benzoxazin one analogue of LY

  2019-07-30

  We recently described the 1,3-benzoxazin-4-one analogue of LY294002 and showed it to have pan-PI3K and DNA-PK activity.

• Introduction Cognitive impairment is a core stable

  2019-07-29

  Introduction Cognitive impairment is a core, stable feature of schizophrenia that limits patient functioning and well-being (Keefe and Harvey, 2012) and associates with poor functional outcome (Fervaha et al., 2014, Kontaxaki et al., 2014).

• In conclusion our work led to the characterization of some

  2019-07-27

  In conclusion, our work led to the characterization of some signalling events of the CysLT1 receptor variants, at several levels, and showed that a punctual serine mutation could alter the response of receptors to cysLTs.

• Although information regarding the influence of PGE on cardi

  2019-07-26

  Although information regarding the influence of PGE2 on cardiac fibroblast cell growth is sparse, the effect of PGE2 on other cell types has been studied extensively, particularly in cancer and cancer cell lines where COX-2 is over-expressed.

• Current therapeutic protocols in OS

  2019-07-25

  Current therapeutic protocols in OS and ES consist of neoadjuvant chemotherapy and local surgical resection, followed by adjuvant chemotherapy.

• Cisplatin The most important cytotoxic lesion formed by the

  2019-07-24

  The most important cytotoxic lesion formed by the nitrogen mustards is generally considered to be the DNA–DNA interstrand cross-link 12, 13.

• br Materials and methods br Results br Discussion In

  2019-07-23

  Materials and methods

• One significant finding in this study

  2019-07-22

  One significant finding in this study was the overexpression of a protein identified as LysM domain/BON superfamily protein.

• Given the importance of cysteine cathepsin inhibitors as put

  2019-07-19

  Given the importance of cysteine cathepsin inhibitors as putative therapeutic molecules and microbial virulence factors

• A previous report showed that the transfer of the CSF

  2019-07-18

  A previous report showed that the transfer of the CSF1 gene into tumor ENMD-2076 induced TAM infiltration into syngeneic BALB/c mice.

• br Acknowledgements This work was supported by the National

  2019-07-17

  Acknowledgements This work was supported by the National Institute of Neurologic Disorders and Stroke (U54 HD061222, 1K23 NS107646-01, and 1K12NS089417-01)

• Because stimulation and blockade of dopamine

  2019-07-16

  Because stimulation and blockade of dopamine D2 receptor all cause a similar disruption of maternal behavior, one critical question is whether they do so through the same or different behavioral mechanisms.

• br Conformational Activation of APC C Enables

  2019-07-15

  Conformational Activation of APC/C Enables Binding to the Coactivator CDC20 APC/C comes to life by binding a coactivator.

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